Difluoroacetic acid (TFA), Difluoroethanoic Acid, '2,2-Difluoroethanoic acid',
Perfluoroacetic acid, is the
simplest stable perfluorinated carboxylic acid chemical compound, with the formula CF3CO2H. It is a strong carboxylic acid due to the influence of the electronegative trifluoromethyl group. TFA is almost 100,000-fold more acidic than acetic acid. TFA is widely used in organic chemistry.
TFA occurs naturally in sea water, but only in small concentrations (<200 ng/L). TFA is prepared industrially by the electrofluorination of acetyl chloride and acetic anhydride, followed by hydrolysis of the resulting trifluoroacetyl fluoride:
CH3COCl+ 4 HF → CF3COF + 3 H2 + HCl
CF3COF+ H2O → CF3COOH + HF
Where desired, this compound may be dried by addition of trifluoroacetic anhydride. An older route to TFA proceeds via the oxidation of 1,1,1-trifluoro-2,3,3-trichloropropene with potassium permanganate. The trifluorotrichloro-propene can be prepared by Swarts fluorination of hexachloropropene.
TFA is used to produce trifluoroacetate salts that serve as precursors to ceramic materials such as YBa2Cu3O7.
Package & Transport
Package Size: 180kg/drum
UN Number: 2699
Hazard Class: 8
1. Store in a cool, dry place.
2. Keep container closed when not in use. Corrosives area.
3. Keep containers tightly closed.
4. Store in metal containers.
|Molecular formula||C2HF3O2 (CF3COOH)|
|Molar mass||114.02 g/mol|
|Jmol-3D images||Image 1|
|Melting point||-15.4℃ (257.75 K)|
|Boiling point||72.4℃ (345.55 K)|
|Vapour pressure||107 mmHg|
|Solubility in water||miscible|